2-BROMO-1-PHENYL-PENTAN-1-ONE CAS 49851-31-2

2-Bromo-1-Phenyl-Pentan-1-One is a bromo ketone with the molecular formula C9H11BrO. It features a bromine atom attached to the alpha position of a phenyl-pentanone structure. The structure of this compound contributes to its reactivity and versatility in organic synthesis.

1. Molecular Formula: C9H11BrO

2. CAS Number: 49851-31-2

3. Appearance: White to off-white crystalline powder.

4. Purity: 99% (High purity for research and industrial applications).

5. Solubility: Soluble in organic solvents like ethanol, acetone, and chloroform.

This compound’s molecular structure, with a phenyl group attached to a pentanone backbone, makes it a suitable building block for further chemical modifications.

2-Bromo-1-Phenyl-Pentan-1-One is a versatile intermediate used in various chemical and pharmaceutical processes.

1. Steroid Synthesis: This compound is primarily used as a precursor in the synthesis of anabolic steroids and related compounds. Its ability to undergo bromination reactions and other transformations makes it essential in the production of bioactive steroids.

2. Pharmaceutical Intermediates: Due to its reactive nature, 2-Bromo-1-Phenyl-Pentan-1-One is used in the production of several pharmaceutical compounds and drug intermediates, particularly those related to hormonal therapies and steroid-based medications.

3. Research and Development: It is an important reagent in medicinal chemistry and organic synthesis, often used by researchers and scientists in the development of new bioactive molecules and pharmaceutical substances.

4. Chemical Reactions: This compound can undergo several important reactions, such as nucleophilic substitution, reduction, and formation of carbon-carbon bonds, making it a highly useful intermediate for creating a wide range of organic molecules.

The synthesis of 2-Bromo-1-Phenyl-Pentan-1-One involves the bromination of 1-Phenyl-Pentan-1-One in the presence of a suitable bromine source. This reaction introduces a bromine atom at the alpha position relative to the carbonyl group, which can then undergo further chemical transformations to create a variety of bioactive compounds.

1. Bromination Reaction: The bromination of 1-Phenyl-Pentan-1-One is a common method for obtaining 2-Bromo-1-Phenyl-Pentan-1-One. This reaction uses bromine (Br2) in an appropriate solvent, typically under controlled temperature conditions, to ensure selective substitution at the desired position.

2. Further Chemical Reactions: Once synthesized, 2-Bromo-1-Phenyl-Pentan-1-One can undergo a variety of reactions such as reduction, alkylation, or cyclization, depending on the desired end product, especially in the synthesis of complex steroidal compounds.