Cas 62-44-2 Phenacetin
Cas 62-44-2 Phenacetin
Cas 62-44-2 Phenacetin
Cas 62-44-2 Phenacetin
Cas 62-44-2 Phenacetin

Cas 62-44-2 Phenacetin

Phenacetin (CAS: 62-44-2) is a well-known analgesic and antipyretic compound historically used for pain relief and fever reduction. It serves as an important research chemical and pharmaceutical intermediate. Phenacetin is valued for its chemical stability, ease of handling, and role in the synthesis of other medicinal compounds, making it a versatile choice for medicinal chemistry studies.

Chemical Structure and Properties


Phenacetin is an aromatic amide with the molecular formula C10H13NO2. It consists of an acetylated amino group attached to a phenol ether, which contributes to its analgesic and antipyretic properties.

1. Molecular Formula: C10H13NO2

2. CAS Number: 62-44-2

3. Appearance: White crystalline powder

4. Purity: 99% (suitable for research and synthesis)

5. Solubility: Soluble in ethanol, chloroform, and slightly soluble in water

The aromatic amide structure allows Phenacetin to act as a precursor for other pharmacologically active compounds.


Applications and Uses


Phenacetin has been widely used as a research chemical and pharmaceutical intermediate.

1. Analgesic and Antipyretic Research: Phenacetin is used in studies involving pain relief mechanisms and fever reduction, helping researchers develop safer and more effective medications.

2. Pharmaceutical Synthesis: It serves as a precursor in the synthesis of paracetamol (acetaminophen) and other related compounds, making it crucial for medicinal chemistry and drug development.

3. Chemical Reactions: Phenacetin’s amide and ether groups allow it to participate in acetylation, alkylation, and other organic synthesis reactions, enabling the creation of novel chemical entities.

4. Research Tool: Used in academic and industrial research, Phenacetin helps study structure-activity relationships and develop new pharmacologically active molecules.


Safety and Handling


Phenacetin must be handled carefully in a controlled laboratory environment:

1. Protective Equipment: Always use gloves, safety goggles, and a lab coat.

2. Ventilation: Work in a well-ventilated fume hood to avoid inhalation.

3. Storage: Store in a cool, dry place, away from light, heat, and moisture. Keep the container tightly sealed.

4. Disposal: Dispose according to local chemical safety regulations. Avoid environmental contamination.





 


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