Aromasin(Exemestane)-25mg
Aromasin(Exemestane)-25mg
Aromasin(Exemestane)-25mg

Aromasin(Exemestane)-25mg

Aromasin (Exemestane) is a potent aromatase inhibitor used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. By inhibiting the aromatase enzyme, it reduces estrogen levels, which can help prevent the growth of estrogen-dependent breast cancer cells. With its proven efficacy and well-established safety profile, Aromasin provides an essential option for breast cancer management, offering 25mg tablets for convenient dosing.

Mechanism of Action


Aromasin (Exemestane) works by inhibiting the aromatase enzyme, which is responsible for converting androgens into estrogens in the body. Estrogen can stimulate the growth of hormone receptor-positive breast cancer cells. By lowering estrogen levels, Aromasin helps to slow or stop the growth of these cancer cells, making it an effective treatment for postmenopausal women with hormone-sensitive breast cancer.


Indications


Breast Cancer Treatment: Aromasin is indicated for the adjuvant treatment of hormone receptor-positive breast cancer in postmenopausal women. It is often used after surgery and other treatments to reduce the risk of cancer recurrence.

Advanced Breast Cancer: It is also approved for use in the treatment of advanced or metastatic breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy.


Clinical Efficacy


In clinical studies, Aromasin has shown significant improvements in disease-free survival and overall survival rates in women with hormone receptor-positive breast cancer.

In the BIG 1-98 trial, Aromasin demonstrated superior efficacy compared to tamoxifen in reducing the risk of breast cancer recurrence, showing a 12% lower risk of recurrence in patients who took Aromasin.

Additionally, studies have shown that Aromasin is generally well tolerated and has a favorable side effect profile compared to other aromatase inhibitors, such as anastrozole.Aromasin is a key part of the armamentarium in the fight against hormone receptor-positive breast cancer and is highly valued for its ability to reduce the risk of cancer recurrence.




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